makeHistoriProcess control & MES · life sciences
Life sciences · biotech · regulated manufacturing

Empowering biotech manufacturing through intelligent automation.

We specialise in advanced process control and Manufacturing Execution System (MES) solutions built for the life sciences industry — with a deep focus on biotechnology and regulated manufacturing environments.

Validation asks whether the system does what you said. Release asks whether you recorded what you did, and did it under control. We built one model that answers both.

Who we are

makeHistori brings a blend of domain expertise, platform knowledge and innovative thinking to every engagement. We work end-to-end — from initial user requirements through to validated functional specifications — in accordance with GAMP 5 and ISPE best practice, so regulatory compliance and audit-readiness are built in at every stage rather than assembled at the end.

We work across platforms and vendors, and we also build our own. Where a client's operational reality is best served by an established DCS or MES product, that is what we specify and deliver. Where it is better served by a modern, namespace-first architecture, we have built one — VData. The choice stays the client's; the standards work is the same either way.

Our expertise

Process control & MES integration

End-to-end project delivery across process automation and MES landscapes — user requirements, functional and design specification, configuration, and qualification — to GAMP 5 and ISPE best practice.

Platform experience

Emerson DeltaV — batch & continuous control Emerson Syncade — MES, eBR, material tracking Siemens PCS 7 Siemens Opcenter Execution Pharma LIMS · ERP · historians

Cloud-enabled digital transformation

Bridging traditional automation and cloud-native architecture, with depth on the AWS platform stack:

  • Data historisation and contextualisation
  • Scalable, secure storage and analytics
  • Edge computing with Greengrass
  • Modern data lakes and event-driven pipelines

The aim is to unlock insight, improve visibility and enable rapid iteration — inside validated, GxP-compliant environments, not alongside them.

Protocol & connectivity solutions

Designing and implementing robust data flows across the old and the new, so brownfield systems reach modern cloud or on-premises platforms without discarding the investment already made.

Legacy OT

OPC DAOPC UAModbusProfibus

Modern IIoT

MQTTSparkplug BREST APIs

Digital strategy & architecture

Assessing, planning and implementing an architecture that matches your compliance, scalability and digital maturity — without compromising data integrity or operational reliability. That means being honest about the trade-offs between:

  • Traditional Purdue-model architectures (ISA-95 / ISA-88)
  • Modern Unified Namespace (UNS) and IIoT-driven models

Most real plants need a considered path between the two, not a wholesale conversion to either.

Why work with us

ISPE memberWe stay current with evolving industry standards, and contribute to shaping best practice.
GAMP-compliant documentationFrom URS through FAT/SAT to CSV — structured, auditable deliverables.
Biotech-focusedExperience spanning upstream and downstream, from fermentation to fill-finish.
Technology-agnosticSolutions tailored to your operational reality, not constrained by product bias.

The VData suite

Alongside the consulting work we build VData — a family of manufacturing applications that share a single modelled namespace, so the data that runs the plant is the same data that releases the batch.

It rests on one idea: bring the plant's irregular sources into a fixed, modelled Unified Namespace, and build every application on the assumption that the model is there. Signals are mapped and given meaning once — an ISA-95-shaped hierarchy of enterprise, site, area, line and unit, with versioned equipment profiles beneath — and after that, orders, operations, logbooks, review and release all read the same picture of the same plant.

The suite runs today as a working platform used for demonstration and pilot work.

Get in touch

Let's build the future of biotech manufacturing.

We combine industrial-grade engineering with modern digital tools to drive efficiency, traceability and innovation in life sciences manufacturing. Whether you are upgrading legacy systems, designing a new facility, or implementing a cloud-based MES architecture — we can help.

info@makehistori.com